79849-51-7

Upstream product

• 100846-92-2 tert-Butyl-[(2Z,4E,6E,8E)-7-methyl-3-trifluoromethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane 
• 100846-85-3 (5E,7E)-1,1,1-Trifluoro-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-5,7-dien-3-yn-2-one 
• 100846-88-6 (3E,5E,7E)-1,1,1-Trifluoro-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trien-2-one 
• 100846-91-1 (2E,4Z)-6-(tert-Butyl-diphenyl-silanyloxy)-4-trifluoromethyl-hexa-2,4-dienal 
• 100846-84-2 2-((1E,3E)-6,6-Dibromo-3-methyl-hexa-1,3,5-trienyl)-1,3,3-trimethyl-cyclohexene 
• 66556-69-2 (E)-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1-buten-3-yltriphenylphosphonium bromide 
• 3917-41-7 (2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal 
• 82648-66-6 (E)-3-(Diethoxy-phosphorylmethyl)-4,4,4-trifluoro-but-2-enoic acid methyl ester 
• 80367-78-8 (E)-3-Bromomethyl-4,4,4-trifluoro-but-2-enoic acid methyl ester 
• 60244-46-4 (Z)-3-(Trifluormethyl)-2-butensaeure-methylester 
• 79849-49-3 methyl 13-(trifluoromethyl)retinoate 
• 100846-89-7 (2Z,4E,6E,8E)-7-Methyl-3-trifluoromethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid ethyl ester 
• 57630-20-3 methyl [(diethoxyphosphino)oxy]acetate 

Relevant academic research and scientific papers

PREPARATION OF 20,20,20-TRIFLUORORETINAL(13-TRIFLUOROMETHYLRETINAL)

All-trans-20,20,20-trifluororetinal (1) was prepared by two ways.

Fluorinated Retinoids via Crossed Aldol Condensation of 1,1,1-Trifluoroacetone

Piperidine-acetic acid catalyzed crossed aldol condensation of 1,1,1-trifluoroacetone with aryl or α,β-unsaturated aldehydes was found to be a useful method for the preparation of unsaturated trifluoromethyl ketones.Chain extension of these ketones led to several new fluorinated retinoids including the hitherto elusive all-trans isomers of 19,19,19- and 20,20,20-trifluororetinal.