79859-76-0Relevant academic research and scientific papers
Synthesis of 5-Deoxykievitone Dimethyl Ether and Related Isopentenylated Isoflavanones
Jain, A. C.,Nayyar, Naresh K.
, p. 481 - 484 (2007/10/02)
Three different 7-hydroxyisoflavanones (1a, 1b and 1c) have been converted into the corresponding 6'',6''-dimethylpyranoisoflavanones (4a, 4b and 4c) either through their 8-(3,3-dimethylallyl) derivatives (2a, 2b and 2c) or their 1,1-dimethylpropargyl ethers (3a, 3b and 3c).Among them, 2c is the dimethyl ether of naturally occurring 5-deoxykievitone.Attempts to synthesize the natural product itself by this route have been unsuccessful because demethylation of the starting desoxybenzoin (5) gives the corresponding 2-arylbenzofuran derivative (7a).
