79878-55-0Relevant academic research and scientific papers
Cu(i)-Catalyzed oxidative homo-coupling of thiazoline-4-carboxylates: Synthesis of 4,4′-bithiazoline derivatives
Fang, Xinxin,Zhang, Kaifan,Yao, Hequan,Huang, Yue
, p. 8030 - 8034 (2016/09/09)
Cu(i)-Catalyzed oxidative homo-coupling of thiazoline-4-carboxylates with good functional group tolerance has been developed. The methodology presented an efficient method to directly construct vicinal carbon-hetero quaternary centers existing in numerous functional molecules and could be applied to the synthesis of 4,4′-bithiazoles which are difficult to prepare by direct C-H activation.
The Reaction of Nitriles with Mercaptoacetic Acid. A New Synthesis of Thiazole Derivatives
Elnagdi, Mohamed Hilmy,Khalifa, Mohamed Ali Elsayed,Ibraheim, Mohamed Kamal Ahmed,Elmoghayar, Mohamed Riffat Hamza
, p. 877 - 879 (2007/10/02)
The reaction of mercaptoacetic acid with nitriles was investigated.Whereas 4-hydroxythiazole derivative could be obtained from the reaction of benzoylacetonitrile and of ethyl cyanoacetate with mercaptoacetic acid, a bithiazole derivative was obtained on
