79889-64-8Relevant academic research and scientific papers
Synthesis of bridgehead nitrogen heterocycles on a solid surface
Ponnala, Shashikanth,Kumar, S. T. V. S. Kiran,Bhat, Bashir A.,Sahu, Devi Prasad
, p. 901 - 906 (2005)
Bridgehead nitrogen heterocycles were synthesized from heteroaromatic amidines and cyclic or acyclic α-bromoketones under solvent-free conditions at room temperature on a solid surface in excellent yields, which are higher than those obtained with hithert
Iron-catalyzed unprecedented formation of benzo[d]imidazo[2,1-b]thiazoles under solvent-free conditions
Balwe, Sandip Gangadhar,Jeong, Yeon Tae
, p. 107225 - 107232 (2016/11/28)
The unprecedented formation of benzo[d]imidazo[2,1-b]thiazole during iron-catalyzed coupling of 2-aminobenzothiazole, aldehydes with nitroalkane in air has been observed. This unique transformation possibly occurs through a sequential aza-Henry reaction and subsequent intramolecular cyclization, followed by denitration. A variety of substituted benzo[d]imidazo[2,1-b]thiazole are obtained using this protocol.
Imidazobenzothiazoles. 2. New Immunosuppressive Agents
Mase, Toshiyasu,Arima, Hideki,Tomioka, Kenichi,Yamada, Toshimitsu,Murase, Kiyoshi
, p. 386 - 394 (2007/10/02)
A series of 2-phenylimidazobenzothiazole derivatives was prepared and tested for immunological activities.Some of the compounds showed significant suppressive activity of delayed type hypersensitivity (DTH) without inhibition of humoral immunity in mice by oral administration.The most active compound was 2-(m-hydroxyphenyl)imidazobenzothiazole (20).
