79889-79-5Relevant academic research and scientific papers
Benzo[d]imidazo[2,1-b]thiazole-based fluorescent sensor for Zn2+ ion detection
Moradi, Seyed Ershad,Molavipordanjani, Sajjad,Hosseinimehr, Seyed Jalal,Emami, Saeed
, (2019/12/09)
In this study, we have synthesized and evaluated three benzo[d]imidazo[2,1-b]thiazole-based sensors (BIT-1, BIT-2 and BIT-3). Among them, BIT-3 namely 2-(benzo[d]imidazo[2,1-b]thiazol-2-yl)-5-methoxyphenol was introduced as a selective fluorescence chemosensor for Zn2+ ion detection. The presence of zinc ions enhanced fluorescence property of BIT-3 at 404 nm due to formation of a 1:1 complex between the chemosensor and the Zn2+ ion. Control experiments showed that the analogous ions do not have fluorescence enhancement effect and some of them even quench the fluorescence dramatically. The data obtained from UV–vis absorption analysis, fluorescence measurements and 1H NMR spectroscopy approved the interaction between BIT-3 and Zn2+ ion. The sensor probe BIT-3 exhibits a selective fluorescence enhancing property via a chelation-enhanced fluorescence (CHEF) upon addition of Zn2+. Thus, a selective fluorescent chemosensor BIT-3 establishes an important sensing platform for real-time monitoring of Zn2+ ion in aqueous environment.
FeCl3/ZnI2-catalyzed synthesis of benzo[D]imidazo[2,1-b]thiazole through aerobic oxidative cyclization between 2-aminobenzothiazole and ketone
Mishra, Subhajit,Monir, Kamarul,Mitra, Shubhanjan,Hajra, Alakananda
supporting information, p. 6084 - 6087 (2015/01/09)
The FeCl3/ZnI2-catalyzed aerobic oxidative cyclization between 2-aminobenzothiazole and ketone/chalcone for the synthesis of benzo[d]imidazo[2,1-b]thiazole is described. A variety of fused benzoimidazothiazole derivatives are obtained by this protocol.
Imidazobenzothiazoles. 2. New Immunosuppressive Agents
Mase, Toshiyasu,Arima, Hideki,Tomioka, Kenichi,Yamada, Toshimitsu,Murase, Kiyoshi
, p. 386 - 394 (2007/10/02)
A series of 2-phenylimidazobenzothiazole derivatives was prepared and tested for immunological activities.Some of the compounds showed significant suppressive activity of delayed type hypersensitivity (DTH) without inhibition of humoral immunity in mice by oral administration.The most active compound was 2-(m-hydroxyphenyl)imidazobenzothiazole (20).
2-Phenylimidazo [2,1-b]benzothiazole derivatives
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, (2008/06/13)
A novel 2-phenylimidazo[2,1-b]benzothiazole derivative shown by the following formula STR1 or a salt thereof which possesses an immunoregulatory action and is useful as an antiallergic agent, an antiasthmatic, and a suppressant of rejection at tissue tran
