79909-53-8Relevant academic research and scientific papers
SYNTHESIS OF THE β-LACTAM ANTIBIOTIC (+)-THIENAMYCIN VIA AN INTERMEDIATE ?-ALLYLTRICARBONYLIRON LACTONE COMPLEXES
Hodgson, Simon T.,Hollinshead, David M.,Ley, Steven V.
, p. 5871 - 5878 (2007/10/02)
The ?-allyltricarbonyliron lactone complex (7), formed by reaction of E-1,2-epoxy-2-methyl-6,6-dimethoxyhex-3-ene (5) with co-ordinatively unsaturated iron carbonyl species, was reacted with benzylamine to give a lactam complex (8) by an SN'-like mechanis
An Asymmetric Synthesis of Synthetic Intermediates to Thienamycin and Epithienamycins A and B
Kametani, Tetsuji,Nagahara, Takayasu,Ihara, Masataka
, p. 3048 - 3052 (2007/10/02)
An asymmetric synthesis for the synthetic intermediates to carbapenem antibiotics was examined via isoxazoline derivatives prepared by 1,3-dipolar cycloaddition between the nitrile oxide and menthyl crotonate.The (4S)-trans-azetidinone (14) having the ant
