79916-77-1 Usage
Overview
Forsythiaside A is the phenylethanol glycoside component isolated from Forsythia. It has pharmacological effects such as antibacterial, antiviral, antioxidant, anti-infective and antipyretic. It is mainly used for content determination, identification, and pharmacological experiment and so on.
Chemical Properties
This product appears as white crystalline powder. It is easily soluble in water, ethanol and methanol, but insoluble in ether and chloroform.
Pharmacological effects
Forsythoside A has not only antibacterial, anti-infective and antipyretic effects, but also good anti-virus and antioxidant effects.
Preparation
Extract 40 g of crushed forsythia leaves with 1200 mL 55% ethanol (volume fraction) at 74 ° C for 50 min, filter and extract twice. The filtrate was combined and concentrated under reduced pressure at 50 °C to recycle the ethanol, obtaining 665 mL of concentrated solution. 35 mL of absolute ethanol was added to give a forsythia leaf extract containing 5% ethanol (volume fraction). The forsythia leaf extract was adsorbed on a 2.6 cm x 25 cm AB-8 resin column and eluted with 50% ethanol to obtain a forsythia leaf extract. The extract of forsythia leaf was extracted for three times with water-saturated n-butanol. Recycle the n-butanol, and dry to obtain crude product. The crude product was separated in 8 cm x 50 cm C18 reverse phase silica gel column chromatography through elution with 30% methanol. Collect the eluent and obtain the pure compound of forsythoside A under reduced pressure.
Application
It can be used for content determination, identification and pharmacological experiments.
Uses
Forsythoside A is used as an antiinflammatory agent in traditional Chinese medicine.
Biological Activity
extracted from forsythia suspense (thunb.) vahl dried fruit;store the product in sealed, cool and dry condition
Check Digit Verification of cas no
The CAS Registry Mumber 79916-77-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,9,1 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 79916-77:
(7*7)+(6*9)+(5*9)+(4*1)+(3*6)+(2*7)+(1*7)=191
191 % 10 = 1
So 79916-77-1 is a valid CAS Registry Number.
InChI:InChI=1/C29H36O15/c1-3-40-28-29(39,15-6-8-17(31)19(33)11-15)26(38)25(44-21(34)9-5-14-4-7-16(30)18(32)10-14)20(43-28)12-41-27-24(37)23(36)22(35)13(2)42-27/h4-11,13,20,22-28,30-33,35-39H,3,12H2,1-2H3/b9-5+/t13-,20+,22-,23+,24+,25+,26-,27+,28+,29+/m0/s1
79916-77-1Relevant articles and documents
FOUR CAFFEOYL GLYCOSIDES FROM CALLUS TISSUE OF REHMANNIA GLUTINOSA
Shoyama, Yukihiro,Matsumoto, Masami,Nishioka, Itsuo
, p. 1633 - 1636 (1986)
From the methanolic extract of callus tissue of Rehmannia glutinosa four phenolic glycosides and one aliphatic glycoside were isolated.Two of the phenolic glycosides were identified as acteoside and forsythiaside and the structures of the other two were elucidated as 3,4-dihydroxy-β-phenethyl-O-β-D-glucopyranosyl-(1->3)-4-O-caffeoyl-β-D-glucopyranosideand 3,4-dihydroxy-O-β-D-glucopyranosyl-(1->3)-α-L-rhamnopyranosyl-(1->6)-4-O-caffeoyl-β-D-glucopyranoside.
