79917-30-9Relevant academic research and scientific papers
ELECTROCHEMICAL OXIDATION OF TETRAMETHYL ESTERS OF α,α,ω,ω-ALCANETETRACARBOXYLIC ACIDS
Elinson, M. I.,Fedukovich, S. K.,Ugrak, B. I.,Nikishin, G. I.
, p. 1827 - 1833 (2007/10/02)
Cyclization of esters of butane-1,1,4,4- and pentane-1,1,5,5-tetracarboxylic acids during electrolysis in methanol in the presence of NaI produces, with a yield of 95percent, the esters of cyclobutane-1,1,2,2- and cyclopentane-1,1,2,2-tetracarboxylic acids.Under similar conditions, esters of the highest α,α,ω,ω-alkanetetracarboxylic acids undergo iodination and hydroxymethylation due to electrical oxidation of methanol to formaldehyde.During electrolysis in methanol in the presence of NaOAc, the esters of α,α,ω,ω-alkanetetracarboxylic acids undergo effective hydroxymethylation, followed by cyclization into substituted five- and six-member lactones, or tetrahydrofurans when structurally possible.Keywords: α,α,ω,ω-alkanetetracarboxylic acids, lactones, tetrahydrofurans, hydroxymethylation, electrolysis, cyclization, mediators.
