799255-59-7Relevant academic research and scientific papers
METHOD FOR THE PRODUCTION OF PHENYLACETIC ACID DERIVATIVES
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Page/Page column 12-13, (2010/02/09)
Disclosed is a method for producing (S) (+) phenylacetic acid derivatives of general formula (I), wherein R1 represents a linear or branched alkyl radical with 1 to 6 carbon atoms or optionally substituted benzyl while R2 represents methyl, ethyl, or propyl. The inventive method is characterized in that a compound of general formula (II), wherein R1 has the meaning indicated above and R3 represents a nucleofuge, or a suitable salt of a compound of general formula (II) is reacted with a compound of general formula (III), wherein R2 has the meaning indicated above and R4 represents hydrogen or a hydrolytically cleavable nucleofuge, whereupon the optionally provided protective group R4 is eliminated.
