799262-00-3Relevant academic research and scientific papers
New acyclonucleosides: Synthesis and anti-HIV activity
Hadj-Bouazza, Amel,Zerrouki, Rachida,Krausz, Pierre,Laumond, Geraldine,Aubertin, Anne Marie,Champavier, Yves
, p. 1249 - 1263 (2007/10/03)
The synthesis of new acyclic nucleosides is described. These syntheses were accomplished by various methods: glycosylation, selective or total deprotection, oxidation/reduction, chlorination or azidation of hydroxyl groups. The compounds were characterized with NMR, mass and IR spectroscopy. Antiviral properties of these compounds were evaluated on HIV-1 infected cell lines. Copyright Taylor & Francis, Inc.
Selective deprotection of fully benzoylated nucleoside derivatives
Zerrouki, Rachida,Roy, Vincent,Hadj-Bouazza, Amel,Krausz, Pierre
, p. 299 - 303 (2007/10/03)
Selective deprotection of benzoylated hydroxyl groups is one of the crucial problems in the synthesis of nucleoside analogues as well as of other polyfunctional molecules. Copyright
