799267-28-0

Upstream product

• 799267-32-6 tert-butyl (2S,5S)-6-azido-2-benzyloxycarbonylamino-5-hydroxyhexanoate 
• 953073-31-9 O-(3,4,6-tri-O-benzyl-2-O-acetyl-β-D-galactopyranosyl)trichloroacetimidate 
• 799267-27-9 tert-butyl (2S,5S)-6-azido-2-benzyloxycarbonylamino-5-(3,4,6-tri-O-benzyl-2-O-chloroacetyl-β-D-galactopyranosyloxy)hexanoate 

Downstream Products

• 953073-35-3 tert-butyl (2S,5S)-6-azido-2-[benzyl(benzyloxycarbonyl)amino]-5-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)hexanoate 
• 799267-30-4 tert-butyl (2S,5S)-2,6-diamino-5-[α-D-glucopyranosyl-(1->2)-β-D-galactopyranosyloxy]hexanoate 
• 953073-29-5 tert-butyl (2S,5S)-6-amino-2-[benzyl(benzyloxycarbonyl)amino]-5-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)hexanoate 
• 799267-29-1 tert-butyl (2S,5S)-6-azido-2-benzyloxycarbonylamino-5-[(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-β-D-galactopyranosyloxy)]hexanoate 

Relevant academic research and scientific papers

Total synthesis of the collagen glycosylated cross-link β-d-galactopyranosyl-O-pyridinoline and of its unnatural epimer β-d-galactopyranosyl-O-epipyridinoline

A short parallel synthesis of β-d-galactopyranosyl-O-pyridinoline (Gal-PYD), a collagen glycoconjugated cross-link, and of Gal-epiPYD, a (5S)-epimer, useful as internal standard in the analytical evaluation of the natural isomer in human tissue, is report

Hydroxylysine containing glycoconjugates: An efficient synthesis of natural galactosylhydroxylysine (Gal-Hyl) and glucosylgalactosylhydroxylysine (Glu-Gal-Hyl) and of their (5S)-epimers

The paper reports the first chemical synthesis of α-d-glucopyranosyl- (1→2)-β-d-galactopyranosyl-5-O-hydroxylysine, a biological marker of bone resorption and of its unnatural (5S)-epimer, starting from commercial sugars and amino acids. Moreover, the synthetic protocol set-up has resulted in a new procedure for the synthesis of the β-d-galactopyranosyl-5-O- hydroxylysine and its unnatural (5S)-epimer.