799274-07-0 Usage
Uses
Used in Pharmaceutical Synthesis:
5-Fluoro-1,2,3,4-tetrahydro-isoquinoline hydrochloride is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its isoquinoline structure and fluorine atom provide a versatile platform for the development of new drugs with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-Fluoro-1,2,3,4-tetrahydro-isoquinoline hydrochloride is used as a building block for the design and synthesis of novel molecules with potential biological activities. The incorporation of fluorine can alter the physicochemical properties of the molecule, such as lipophilicity and metabolic stability, which may lead to improved drug candidates.
Used in Drug Delivery Systems:
5-Fluoro-1,2,3,4-tetrahydro-isoquinoline hydrochloride may be employed in the development of drug delivery systems, where its fluorinated nature could enhance the solubility, bioavailability, and targeted delivery of therapeutic agents. This could be particularly useful in the design of prodrugs or drug conjugates with improved pharmacokinetic properties.
Used in Fluorinated Compound Research:
As a fluorinated isoquinoline derivative, 5-Fluoro-1,2,3,4-tetrahydro-isoquinoline hydrochloride is used in research to explore the effects of fluorination on the chemical and biological properties of isoquinoline compounds. This can provide insights into the role of fluorine in drug design and help identify new strategies for the development of fluorinated pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 799274-07-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,9,2,7 and 4 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 799274-07:
(8*7)+(7*9)+(6*9)+(5*2)+(4*7)+(3*4)+(2*0)+(1*7)=230
230 % 10 = 0
So 799274-07-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H10FN.ClH/c10-9-3-1-2-7-6-11-5-4-8(7)9;/h1-3,11H,4-6H2;1H
799274-07-0Relevant articles and documents
PRMT5 INHIBITORS
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, (2021/06/26)
The present invention provides a compound of Formula (I) and the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are PRMT5 inhibitors. Also provided are methods of making compounds of Formula I, pharmaceutical compositions comprising compounds of Formula I, and methods of using these compounds to treat cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.
NOVEL TETRAHYDROISOQUINOLINES AND TERAHYDRONAPHTHYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
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Page/Page column 60, (2018/05/24)
The present invention provides novel compounds having the general formula (I): wherein R1, R 2, R 3, U, V, W, X and Y are as described herein, compositions including the compounds and methods of using the compounds.
