799291-51-3

Upstream product

• 586-78-7 para-nitrophenyl bromide 

Downstream Products

• 144221-40-9 3-(4-Bromo-phenyl)-2-(4-nitro-phenyl)-2,3-dihydro-1H-benzo[g]quinazolin-4-one 

Relevant academic research and scientific papers

A novel water-dispersible and magnetically recyclable nickel nanoparticles for the one-pot reduction-Schiff base condensation of nitroarenes in pure water

In this work, a heterogeneous nanocatalyst called Ni-Fe3O4@Pectin~PPA ~ Piconal was first synthesized, which was investigated as a bifunctional catalyst containing nickel functional groups. On the other hand, this Ni-Fe3O4@Pectin~PPA ~ Piconal catalyst in aqueous solvents shows a very effective performance at ambient temperature for the nitroarene reduction reaction with sodium borohydride, for which NaBH4 is considered as a reducing agent. This is a novelty magnetic catalyst that was approved by various methods, including Fourier-transform infrared spectroscopy (FT-IR), X-ray powder diffraction (XRD), Dynamic light scattering (DLS), Transmission electron microscopy (TEM), vibrating sample magnetometer (VSM), Inductively coupled plasma (ICP), Energy-dispersive X-ray spectroscopy (EDX), and Field emission scanning electron microscopy (FESEM) analyses. From the satisfactory results obtained from the reduction of nitrogen, this catalytic system is used for a one-pot protocol containing a reduction-Schiff base concentration of diverse nitroarenes. It was corroborated with the heterogeneous catalytic experiments on the one-pot tandem synthesis of imines from nitroarenes and aldehydes. Finally, the novel Ni-Fe3O4@Pectin~PPA ~ Piconal catalyst could function as a more economically desirable and environmentally amicable in the catalysis field. The favorable products are acquired in good to high performance in the attendance of Ni-Fe3O4@Pectin~PPA ~ Piconal as a bifunctional catalyst. This catalyst can be recycled up to six steps without losing a sharp drop.

Mechanism of Thermal Z/E Isomerization of Substituted N-Benzylideneanilines. Nature of the Activated Complex with an sp-Hybridized Nitrogen Atom

In order to study the mechanism of thermal geometrical isomerization involving a sp2-hybridized nitrogen atom, kinetic effects of substituent, solvent, and pressure were studied in substituted N-benzylideneanilines.The effect of the substituent on the aniline moiety was almost independent of the electronic nature of the benzylidene group, and the results could be described satisfactorily by log (k/k0) = ρ0 + r+(?+ - ?0) + r-(?- - ?0)>, except for the 4-(dimethylamino) group.The r- values were more than twice as large as r0, suggesting strongly that the aniline ring is in conjugation not with the carbon-nitrogen ? bond but with the nitrogen lone pair in the transition state.The lower activation enthalpies and fairly large negative activation entropies observed in N-(4-X-benzylidene)-4-nitroanilines also support this view.When a dimethylamino group exists in the 4-position of the aniline ring, the rate constants observed were larger than that expected from the above equation.This deviation suggests the existence of a reaction route where the two phenyl groups become coplanar in the transition state.Ab initio calculations on selected N-phenylformaldimines and N- benzylideneanilines were performed to characterize the actual relation between both reaction possibilities as alternative and parallel routes, respectively.On the basis of the experimental data, the rate constants for the two inversion isomerizations were estimated by assuming parallel reactions for three cases.