79932-34-6Relevant academic research and scientific papers
An efficient synthesis of thiazolo[3,2-a]pyrimidinones
Ahmad, Nadia M.,Jones, Keith
experimental part, p. 3263 - 3265 (2010/07/10)
A series of thiazolo[3,2-a]pyrimidinones was synthesised in a two-step procedure, using Eaton's reagent to effect cyclisation of 2-aminothiazoles. The use of relatively low temperatures, facile product isolation and short reaction times make this cyclisation procedure a particularly attractive option over more conventional methods.
1-Oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides
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, (2008/06/13)
Antiallergy and antiulcer agents having the formula (I), STR1 and their pharmaceutically acceptable salts, wherein R1 and R2 taken separately are each hydrogen or lower alkyl; and R1 and R2 taken together are alkylene of 3-9 carbon atoms or phenylalkylene of 9-11 carbon atoms, with the proviso that the ring so formed is between 5- and 8-membered; acids of the formula (II), STR2 wherein R1 and R2 are as defined above and R3 is hydrogen, which are useful as intermediates for compounds of the formula (I), but in many instances also possess the same useful biological activity as do formula I compounds; and intermediates of the formula II wherein R1 and R2 are defined as above, and R3 is alkyl of 1 to 4 carbon atoms, carbalkoxy of 2 to 5 carbon atoms, carbophenoxy or carbobenzoxy, are also described.
