79950-67-7

Upstream product

• 63316-81-4 4-bromophenyl methylthiomethyl ether 
• 106-41-2 4-bromo-phenol 
• 121824-43-9 1-((methylsulfinyl)methoxy)-4-bromobenzene 

Downstream Products

• 79950-78-0 (S)-3-[3-(4-Bromo-benzyloxymethyl)-3H-imidazol-4-yl]-2-tert-butoxycarbonylamino-propionic acid methyl ester 

Relevant academic research and scientific papers

Syntheses of Sulfinylmethyl Ethers and Conversion of these into Halomethyl and Acyloxymethyl Ethers

Halomethyl ethers can be prepared from sulfinyl ethers by cleavage of the carbon-sulfur bond with thionyl chloride, acetyl chloride or trimethylsilyl halides.In the presence of alkenyl groups in the substrate, acetyl chloride is the reagent of choice.Trifluoroacetic anhydride reacts in the same manner to form the trifluoroacetoxymethyl ether.With acetic anhydride, catalysis by methanesulfonic acid was required.At elevated temperatures in the presence of sodium acetate the products were formed by the Pummerer rearrangement.