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(4E)-4-[(4-[bis(2-chloroethyl)amino]phenylamino)methylidene]-5-(hydroxymethyl)-2-methylpyridin-3(4H)-one, also known as Temozolomide, is an oral chemotherapy drug that belongs to the class of alkylating agents and is specifically a DNA-methylating imidazotetrazine derivative. It is used to treat certain types of brain tumors, including glioblastoma multiforme and anaplastic astrocytoma, by disrupting the growth and spread of cancer cells in the body.
Used in Oncology:
Temozolomide is used as a chemotherapy agent for the treatment of brain tumors such as glioblastoma multiforme and anaplastic astrocytoma. It works by methylating DNA and causing DNA damage, which leads to the death of cancer cells and inhibits their growth and spread.
Used in Combination Therapy:
Temozolomide is often used in combination with radiation therapy to enhance the effectiveness of treatment for brain tumors. This combination therapy helps to increase the sensitivity of cancer cells to radiation, leading to a more significant reduction in tumor size and improved patient outcomes.
Used in Single-Agent Treatment:
In some cases, Temozolomide may be used as a single-agent treatment for patients who are not suitable candidates for combination therapy or have recurrent brain tumors. It can help to manage the symptoms and slow down the progression of the disease.
Common side effects of Temozolomide may include nausea, vomiting, diarrhea, and fatigue. It may also cause a decrease in blood cell counts, which can increase the risk of infection and bleeding. However, these side effects can be managed with appropriate supportive care and medical interventions.

79967-32-1

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79967-32-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 79967-32-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,9,6 and 7 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 79967-32:
(7*7)+(6*9)+(5*9)+(4*6)+(3*7)+(2*3)+(1*2)=201
201 % 10 = 1
So 79967-32-1 is a valid CAS Registry Number.

79967-32-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (4E)-4-[[4-[bis(2-chloroethyl)amino]anilino]methylidene]-5-(hydroxymethyl)-2-methylpyridin-3-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:79967-32-1 SDS

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