799767-80-9Relevant academic research and scientific papers
CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS
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Paragraph 00265; 00270, (2019/02/25)
The present disclosure relates to modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25, pharmaceutical compositions comprising the inhibitors, and methods of using the inhibitors. The modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25 can be useful in the treatment of cancers, among other ailments.
Chemoenzymatic synthesis of (3S,4S)- and (3R,4R)-3-methoxy-4- methylaminopyrrolidine
Kamal, Ahmed,Shaik, Ahmad Ali,Sandbhor, Mahendra,Malik, M. Shaheer,Kaga, Harumi
, p. 8057 - 8059 (2007/10/03)
Facile chemoenzymatic enantioselective synthesis of (3S,4S)-3-methoxy-4- methylaminopyrrolidine, a key intermediate for a new quinolone antitumor compound AG-7352 has been described. This methodology illustrates the preparation of 3-azido-1-benzyloxycarbo
