Maytansinoid dM4, also known as Maytansine derivative DM4, is a potent cytotoxic agent derived from the natural product Maytansine. It possesses significant anticancer properties and is characterized by its ability to inhibit microtubule assembly, leading to cell cycle arrest and apoptosis in cancer cells.
799840-96-3
Post Buying Request-
-
Basic information
- Product Name: Maytansinoid dM4
- Synonyms: Maytansinoid dM4;N2'-deacetyl-n2'-(4-Mercapto-4-Methyl-1-oxopentyl)-6-MethylMaytansine
- CAS NO:799840-96-3
- Molecular Formula: C39H56ClN3O10S
- Molecular Weight: 794.39
- EINECS: N/A
- Product Categories: N/A
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: 940.2±65.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.28±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 9.83±0.70(Predicted)
- CAS DataBase Reference: Maytansinoid dM4(CAS DataBase Reference)
- NIST Chemistry Reference: Maytansinoid dM4(799840-96-3)
- EPA Substance Registry System: Maytansinoid dM4(799840-96-3)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 799840-96-3(Hazardous Substances Data)
799840-96-3 Suppliers
Recommended suppliers
799840-96-3 Usage
Uses
Used in Pharmaceutical Industry:Maytansinoid dM4 is used as an antibody-drug conjugate (ADC) for the targeted treatment of cancer. It is designed to selectively deliver the cytotoxic payload to cancer cells, minimizing damage to healthy cells and reducing side effects. This targeted approach enhances the therapeutic index and effectiveness of cancer treatment.
As an ADC, Maytansinoid dM4 is linked to a monoclonal antibody that specifically recognizes and binds to a unique antigen expressed on the surface of cancer cells. Upon binding, the ADC is internalized by the cancer cell, where the Maytansinoid dM4 is released and exerts its cytotoxic effects, leading to the destruction of the cancer cell while sparing healthy cells.
This innovative approach has shown promise in the treatment of various types of cancer, including solid tumors and hematological malignancies, offering a more effective and less toxic alternative to traditional chemotherapy.
Check Digit Verification of cas no
The CAS Registry Mumber 799840-96-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,9,8,4 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.Calculate Digit Verification of CAS Registry Number 799840-96:
(8*7)+(7*9)+(6*9)+(5*8)+(4*4)+(3*0)+(2*9)+(1*6)=253
253 % 10 = 3
So 799840-96-3 is a valid CAS Registry Number.
799840-96-3Upstream product
799840-96-3Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 799840-96-3
Maytansinoid dM4
