80004-04-2 Usage
General Description
(S)-1,4,7,10,13,16-Hexaoxacyclooctadecane-2-methanol, also known as crown-6 ether, is a chemical compound with the molecular formula C12H24O6. It is a cyclic polyether that consists of six oxygen atoms arranged in a crown-like structure. Crown-6 ether is commonly used as a phase transfer catalyst in organic synthesis and as a complexing agent in coordination chemistry. It is also used in the extraction of metal ions and as a component in the separation and purification of chemicals. Additionally, it has applications in the field of supramolecular chemistry and as a host molecule in host-guest chemistry. Crown-6 ether is known for its ability to selectively bind cations, particularly alkali and alkaline earth metal ions, making it valuable in various chemical processes and research applications.
Check Digit Verification of cas no
The CAS Registry Mumber 80004-04-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,0,0 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 80004-04:
(7*8)+(6*0)+(5*0)+(4*0)+(3*4)+(2*0)+(1*4)=72
72 % 10 = 2
So 80004-04-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H26O7/c14-11-13-12-19-8-7-17-4-3-15-1-2-16-5-6-18-9-10-20-13/h13-14H,1-12H2/t13-/m0/s1
80004-04-2Relevant articles and documents
Biomimetic Studies Using Artificial Systems. II. Enantioselective Thiolysis of D- or L-α-Amino Acid Ester Salts by Thiol-Bearing Chiral Crown Ethers as an Enzyme Model
Sasaki, Shigeki,Kawasaki, Motoji,Koga, Kenji
, p. 4247 - 4266 (2007/10/02)
The rates of transacylation were studied between thiol-bearing chiral crown ethers (1-10) and α-amino acid p-nitrophenyl ester salts.Enantioselectivities, kD/kL ratios, of 6.5 for valine ester salt, 8.7 for phenylalanine ester salt, and 7.7 for valine ester salt were achieved by 1, 5, and 8, respectively.Saturation phenomena of rate acceleration depending on crown concentration were observed and analysis of these data revealed that the chiral recognition occurs in the step of liberation of p-nitrophenol by intra-complex thiolysis, not in the complex-forming step.A possible mechanism for the anantioselectivity is proposed on the basis of the kinetic data.Keywords - crown ether; transacylation; pseudo-first-order rate constant; enantioselectivity; thiolysis; intra-complex reaction; enzyme model
