80009-10-5Relevant academic research and scientific papers
Stereochemical studies on medicinal agents. 25. Absolute configuration and analgetic potency of beta-1,2-dimethyl-4-phenyl-4-(propionyloxy)piperidine enantiomers
Fries,Dodge,Hope,Portoghese
, p. 9 - 12 (1982)
Enantiomers of β-1,2-dimethyl-4-phenyl-4-(propionyloxy)piperidine (4) were employed as probes to demonstrate that opioid receptors are capable of distinguishing between the enantiotopic edges (the Ogston effect) of the piperidine ring. These enantiomers,
