Targesin, also known as sorafenib, is a kinase inhibitor with a primary function in treating advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). It operates by targeting and inhibiting the activity of multiple kinases that play a role in tumor cell proliferation and angiogenesis, which is the formation of new blood vessels to nourish and oxygenate tumors. By obstructing these pathways, targesin can effectively slow or halt the growth of cancer cells, contributing to the reduction of tumor size and the enhancement of overall patient survival rates in those with RCC or HCC.
8002-27-5
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Basic information
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
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- Solubility: N/A
- CAS DataBase Reference: targesin(CAS DataBase Reference)
- NIST Chemistry Reference: targesin(8002-27-5)
- EPA Substance Registry System: targesin(8002-27-5)
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Safety Data
- Hazard Codes: N/A
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- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 8002-27-5(Hazardous Substances Data)
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8002-27-5 Usage
Uses
Used in Oncology:Targesin is used as an anticancer agent for the treatment of advanced renal cell carcinoma and hepatocellular carcinoma. It functions by inhibiting the activity of multiple kinases that are crucial for tumor cell proliferation and the formation of new blood vessels that supply tumors, thereby slowing down or stopping the growth of cancer cells.
Used in Pharmaceutical Development:
Targesin is utilized in the development of pharmaceuticals targeting cancer treatment, specifically for diseases like renal cell carcinoma and hepatocellular carcinoma. Its role in inhibiting the activity of multiple kinases involved in tumor growth and angiogenesis makes it a valuable component in the creation of cancer therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 8002-27-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 8,0,0 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.Calculate Digit Verification of CAS Registry Number 8002-27:
(6*8)+(5*0)+(4*0)+(3*2)+(2*2)+(1*7)=65
65 % 10 = 5
So 8002-27-5 is a valid CAS Registry Number.
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