80027-52-7

Upstream product

• 4792-33-0 4-methoxyphthalide 
• 60407-04-7 2-formyl-3-methoxy-benzoic acid 
• 77-78-1 dimethyl sulfate 
• 84390-99-8 2,3-dihydro-3-hydroxy-4-methoxy-2-methylisoindol-1-one 
• 18713-43-4 3-hydroxy-4-methoxy-1(3H)-isobenzofuranone 
• 74-88-4 methyl iodide 

Downstream Products

• 53015-08-0 2-formyl-6-methoxy-benzoic acid 
• 80241-82-3 methyl 2-formyl-6-methoxybenzoate 
• 80027-67-4 2-[6-Hydroxy-1,4-dimethoxy-6-(2-methyl-[1,3]dioxolan-2-yl)-5,6,7,8-tetrahydro-naphthalen-2-ylmethyl]-3-methoxy-benzoic acid 
• 80027-66-3 6-(2-carboxy-6-methoxybenzyl)-1,2,3,4-tetrahydro-8-methoxynapthalene-2,5-diol 
• 80027-62-9 6-(2-carboxy-6-methoxybenzyl)-1,2,3,4-tetrahydro-5-hydroxy-8-methoxynaphthalene-2-carboxylic acid 
• 80027-54-9 2-acetyl-6-(2-carboxy-6-methoxybenzyl)-1,2,3,4-tetrahydro-8-methoxy-5-naphthol 
• 87702-85-0 2-Acetyl-6-(2-carboxy-6-methoxybenzyl)-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene 

Relevant academic research and scientific papers

Highly enantioselective synthesis of 2,3-dihydro-1 H-imidazo[2,1-a isoindol-5(9b H)-ones via catalytic asymmetric intramolecular cascade imidization-nucleophilic addition-lactamization

Highly enantioselective catalytic asymmetric intramolecular cascade imidization-nucleophilic addition-lactamization of N1-alkylethane-1,2-diamine with methyl 2-formylbenzoate catalyzed by a chiral phosphoric acid represents the first efficient method for the preparation of medicinally interesting chiral 2,3-dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-ones with high yields and excellent enantioselectivities. This strategy has been shown to be quite general toward various methyl 2-formylbenzoates.

Anthracyclines. Part 1. The Synthesis of Racemic Daunomycinone and Some Related Tetrahydronaphthacenequinones

New tetrahydronaphthacenequinones, which are related in structure to the aglycones of the antitumor drugs adriamycin and daunomycin, have been synthesised.Racemic daunomycinone has been prepared by a new, mild procedure utilising a phthalide intermediate