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ERGTOXIN, a potent neurotoxin predominantly found in the ergot fungus, functions as an antagonist of voltage-gated potassium channels. This action disrupts nerve signals, potentially leading to paralysis and other neurological effects in animals. Additionally, ERGTOXIN exhibits vasoconstrictive properties, which can result in reduced blood flow and tissue damage. Given its high toxicity, it poses a significant risk to both livestock consuming contaminated grains and humans who might inadvertently ingest it through contaminated food or drink. Vigilant monitoring and control of ERGTOXIN in agricultural products are crucial to prevent potential harm to both animals and humans.

8006-25-5

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8006-25-5 Usage

Uses

Used in Research and Development:
ERGTOXIN is used as a research tool for studying the effects of voltage-gated potassium channel antagonists on nerve signal transmission and neurological functions. Its potent toxicity makes it a valuable compound for understanding the mechanisms of action and potential therapeutic interventions in various neurological disorders.
Used in Pharmaceutical Development:
Although ERGTOXIN itself is highly toxic, its properties as a potassium channel antagonist can be leveraged in the development of drugs targeting specific ion channels for the treatment of certain conditions. Researchers can use ERGTOXIN as a starting point to design safer and more effective drugs with similar mechanisms of action.
Used in Agricultural Monitoring:
ERGTOXIN is used as a biomarker for detecting the presence of toxic fungi in agricultural products, such as grains. Regular testing for ERGTOXIN can help ensure the safety of livestock feed and prevent the contamination of the food supply chain, protecting both animals and humans from potential harm.
Used in Toxicology Studies:
ERGTOXIN serves as a model compound in toxicology studies, providing insights into the mechanisms of action, toxicokinetics, and toxicodynamics of potent neurotoxins. Understanding the effects of ERGTOXIN on biological systems can contribute to the development of antidotes and countermeasures against similar toxins.
Used in Educational Settings:
ERGTOXIN can be utilized as a teaching tool in educational settings, such as universities and research institutions, to illustrate the principles of toxicology, neurobiology, and ion channel physiology. Studying ERGTOXIN can help students gain a deeper understanding of the complex interactions between toxins and biological systems.

Check Digit Verification of cas no

The CAS Registry Mumber 8006-25-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 8,0,0 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 8006-25:
(6*8)+(5*0)+(4*0)+(3*6)+(2*2)+(1*5)=75
75 % 10 = 5
So 8006-25-5 is a valid CAS Registry Number.

8006-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Ecboline

1.2 Other means of identification

Product number -
Other names ERGOTOXINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:8006-25-5 SDS

8006-25-5Upstream product

8006-25-5Downstream Products

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