8006-64-2 Usage
Description
Turpentine oil is a fluid derived from live trees, primarily pines, consisting of terpenes such as monoterpenes, alpha-pinene, beta-pinene, careen, camphene, dipentene, and terpinolene. It serves as a solvent and a source of materials for organic synthesis.
Used in Paint and Varnish Industry:
Turpentine oil is used as a solvent and thinner for oil-based paints and varnishes, aiding in the manufacturing process.
Used in Organic Synthesis:
Turpentine oil is used as a source material for synthesizing fragrant chemical compounds like camphor, linalool, and alpha-terpineol.
Used in Nanotechnology:
It is utilized for large-scale synthesis of bundles of aligned carbon nanotubes.
Used as a Natural Flavoring Agent:
Turpentine oil serves as a food additive, providing natural flavoring.
Used in Pesticide Synthesis:
It is used to synthesize pesticides for agricultural and other applications.
Used in Dental Treatment:
Turpentine oil facilitates endodontic retreatment in dental procedures.
Used in Cleaning Agents:
Traditionally, turpentine oil has been applied as a cleaning agent for paints, lacquers, rubber, and varnishes, as well as for disinfectants and insecticides.
Used in Pharmaceutical Industry:
It is used in the pharmaceutical industry for various applications, including perfumery, sprays, deodorizers, and stimulating ointments.
Used in Fragrance Production:
Derived terpenes like camphor, citral, linalool, and menthol from turpentine oil are employed in the creation of other fragrances.
Used in Polish Preparation:
Turpentine oil is utilized in the preparation of shoe, stove, and furniture polishes.
Used in Aroma Chemicals Manufacturing:
It is a source of pine oil and used in the manufacture of synthetic camphor and terpin hydrate.
Production Methods
Gum turpentine is the steam-volatile fraction of pine tree
pitch.Wood turpentine is obtained from waste wood chips or
sawdust. Sulfate turpentine is a by-product in paper manufacture.
Air & Water Reactions
Highly flammable. Insoluble in water.
Reactivity Profile
WOOD TURPENTINE reacts with oxidizing agents. Calcium hypochlorite was placed in a turpentine container, thought to be empty. Reaction with the residual turpentine resulted in an explosion within a few minutes [Benson 1967]. Reacts violently with chromic anhydride [Haz. Chem. Data 1967 p. 68]. Reacts with stannic chloride producing heat and sometimes flame [Mellor 7:430 1946-47]. May also react exothermically with reducing agents to produce gaseous hydrogen.
Health Hazard
Occupational exposures to turpentine cause adverse health effects on absorption through the skin, lungs, and intestine. The vapor of turpentine causes severe irritation to the nose, eyes, and respiratory system has a whole. Aspiration of liquid turpentine causes direct irritation to the lungs and results in pulmonary edema and hemorrhage. It also causes dermatitis, eczema, and hypersensitivity among occupational workers. Splashing of liquid turpentine in the eyes causes corneal burns. Turpentine is also known to cause skin eruption, irritation to the gastrointestinal tract, kidney and bladder damage, delirium, ataxia, and benign skin tumor.
Flammability and Explosibility
Flammable
Safety Profile
An experimental poison
by intravenous route. Moderately toxic to
humans by ingestion. Mildly toxic
experimentally by ingestion and inhalation.
Human systemic effects by ingestion and
inhalation: conjunctiva irritation, other
olfactory and eye effects, hallucinations or
distorted perceptions, antipsychotic,
headache, pulmonary, and kidney changes.
A human eye irritant. Irritating to skin and
mucous membranes. Can cause serious
irritation of kidneys. Questionable
carcinogen with experimental tumorigenic
data. A common air contaminant. A very
dangerous fire hazard when exposed to heat
or flame; can react vigorously with oxidizing
materials. Avoid impregnation of
combustibles with turpentine. Keep cool
and ventilated. Spontaneous heating is
possible. Moderate explosion hazard in the
form of vapor when exposed to flame; can
react violently with Ca(OCl)2, Cl2, CrO3, Cr-
(OCl)2, SnCl4, hexachloromelamine,
trichloromelamine. To fight fire, use foam,
CO2, dry chemical. When heated to
decomposition it emits acrid smoke and
irritating fumes.
Potential Exposure
Turpentines have found wide use as
chemical feedstock for the manufacture of floor, furniture,
shoe, and automobile polishes; camphor, cleaning materials;
inks, putty, mastics, cutting and grinding fluids; paint
thinners; resins, and degreasing solutions. Recently,
alpha-and beta-pinenes, which can be extracted, have
found use as volatile bases for various compounds. The
components d-α-pinene and 3-carene, or their hydroperoxides,
may be the cause of eczema and toxic effects of
turpentine.
Carcinogenicity
When turpentine was applied to
the skin, tumor growth was promoted in the rabbit, but not in
the mouse.
Environmental Fate
Routes and Pathways
Humans can be affected by one of several possible exposure
routes, as follows: flavoring agents in candies and chewing
gums; manufacture of turpentine oil, gum rosin, and synthetic
pine oil; application of insecticides, disinfectants, human and
veterinary medicines, ointments, deodorizers, and perfumes;
and workers in manufacturing of shoe, stove, furniture,
synthetic camphor and menthol, cleaning materials, inks,
grinding fluids, and thinners.
Partition Behavior in Water, Sediment, and Soil and
Physicochemical Properties
Table 2 shows the physicochemical properties and other
behavior of turpentine oil.
Environmental Persistency and Long-Range Transport
Turpentine is completely degradable and also does not represent
a hazard to plants treated by wastewater, because of solubility
limitations. When it is released into the environment, spills or
leaks should be completely cleaned up. Best management
practices at facilities are needed in order to reduce the amount of
turpentine released to the air during turpentine production.
Turpentine is not classified as an air-polluting substance,
according to the US Clean Air Act, because its terpenes are
completely degraded by natural processes within a few days
depending on its concentration, air temperature, and existence
of bacteria. Turpentine is recognized safe for ozone depleting or
global warming.
According to the US Occupational Safety and Health
Administration (OSHA), exposures to turpentine oil may occur
through solvents, industrial coatings, and starting material for
other compounds, and during pulp and paper processes.
People and hobbyists can be exposed through foods, personal
care products, household products, external and internal
medications, paints, and varnishes.
Shipping
UN1299 Turpentine, Hazard Class: 3; Labels: 3-
Flammable liquid.
Toxicity evaluation
Ingestion, inhalation, and skin penetration are three common
exposure routes of turpentine, due to its lipophilic properties,
leading to easy accumulation in fats. As observed in rats,
spleen, kidneys, brain, and peripheral fats are the main sites of
local acquisition of turpentine. Liver microsomal epoxide
hydrase and uridine diphosphoglucuronosyl transferase activities were elevated during chronic turpentine exposures.
Toxicity of turpentine may also be attributed to its degraded
compounds. For instance, crude sulfate turpentine is usually
converted into methyl mercaptan. The terpene constituents of
turpentine (typically unsaturated hydrocarbons) may react
with oxidants (ozone) of indoor air to generate strong irritant
compounds such as formaldehyde or radicals.
Incompatibilities
Forms an explosive mixture with air.
Violent reaction with strong oxidizers, especially chlorine;
chromic anhydride; stannic chloride; chromyl chloride.
Precautions
During handling of turpentine, occupational workers should always use protective clothing, rubber gloves, and face masks to avoid adverse health effects to the skin and respiratory tract.
References
Kalpana Awasthi, et al. "Large scale synthesis of bundles of aligned carbon nanotubes using a natural precursor: turpentine oil." Journal of Experimental Nanoscience 5.6(2010):498-508.
Bai, Yun. "The general situation of flavor from turpentine oil." China Food Additives (2006).
Pakdel, H, S. Sarron, and C. Roy. "alpha-Terpineol from hydration of crude sulfate turpentine oil. " Journal of Agricultural & Food Chemistry 49.9(2001):4337-41.
Dong-Mei, L. I., et al. "Study on synthesis of high purity α-terpineol from turpentine oil." Modern Chemical Industry (2008).
Armstrong, Henry E. "XXXV.—Studies of the terpenes and allied compounds. The nature of turpentine oils, including that obtained from Pinus khasyana." Journal of the Chemical Society Transactions 59:311-315.
Guilbert, J., et al. "Anti-flatulence treatment and status epilepticus: a case of camphor intoxication." Emergency Medicine Journal Emj 24.12(2007):859.
Qin, Lang, and Y. M. Wang. "Application of Turpentine Oil in Synergist and Pesticide and Its Progress." Fine & Specialty Chemicals (2005).
Kaplowitz, G. J. "Clinical uses of rectified turpentine oil." International Endodontic Journal 29.2(1996):93.
Check Digit Verification of cas no
The CAS Registry Mumber 8006-64-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 8,0,0 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 8006-64:
(6*8)+(5*0)+(4*0)+(3*6)+(2*6)+(1*4)=82
82 % 10 = 2
So 8006-64-2 is a valid CAS Registry Number.
