80061-25-2

Usage

InChI:InChI=1/C22H26FN3O2/c1-14-10-12-25-21-18(26-15(2)5-4-11-24)13-19(27-3)22(20(14)21)28-17-8-6-16(23)7-9-17/h6-10,12-13,15,26H,4-5,11,24H2,1-3H3

Upstream product

• 81358-81-8 4-methyl-5-hydroxy-6-methoxy-8-nitroquinoline 
• 81358-92-1 5-chloro-6-methoxy-4-methyl-8-nitroquinoline 
• 82349-26-6 5-(4-Fluorophenoxy)-6-methoxy-4-methyl-8-nitroquinoline 
• 160088-53-9 N-(5-chloro-4-methoxy-2-nitrophenyl)-acetamide 
• 1361025-89-9 C₁₃H₁₁FN₂O₄*ClH 
• 107095-81-8 C₁₅H₁₃FN₂O₅ 
• 64992-96-7 4-methyl-5,6-dimethoxy-8-nitroquinoline 
• 82333-45-7 8-Amino-5-(4-fluorophenoxy)-6-methoxy-4-methylquinoline 
• 371-41-5 4-Fluorophenol 
• 82429-77-4 5-(4-fluorophenoxy)-6-methoxy-4-methyl-8-((4-phthalimido-1-methylbutyl)amino)quinoline 

Downstream Products

• 106363-50-2 C₄H₆O₄*C₂₂H₂₆FN₃O₂ 

Relevant academic research and scientific papers

Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs

8-Aminoquinolines (8-AQs) are important class of anti-infective therapeutics. 5-Phenoxy 8-aminoquinoline analogs have shown improved metabolic stability compared to primaquine. In view or predictive role of monoamine oxidases (MAO) in metabolism of 8-amin

Antimalarials. 14. 5-(Aryloxy)-4-methylprimaquine Analogues. A Highly Effective Series of Blood and Tissue Schizonticidal Agents

A series of five 5-(aryloxy)-4-methylprimaquine analogues has been prepared and evaluated for antimalarial activity.The compounds were tested for suppressive activity against Plasmodium berghei in mice and for radical curative activity against Plasmodium