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Upstream product

• 150-13-0 4-amino-benzoic acid 
• 7585-39-9 β‐cyclodextrin 

Relevant academic research and scientific papers

Crystal structure determination of the β-cyclodextrin-p-aminobenzoic acid inclusion complex from powder X-ray diffraction data

The 1:1 inclusion complex of β-cyclodextrin and p-aminobenzoic acid was prepared and characterized by TG-DTA. The crystal structure of the complex was solved directly from powder X-ray diffraction data using the direct space approach and refined using Rietveld refinement techniques. The complex crystallizes in monoclinic P21 space group, with unit cell parameters a = 20.7890 , b = 10.2084 , c = 15.1091 , β = 110.825°, V = 2997 3. The amino group is located at the wide side of the β-cyclodextrin cavity, forming hydrogen bonds with β-cyclodextrin, and the carboxyl group is located at the narrow side. The crystallographic data obtained from powder diffraction data were compared with the single crystallographic data, and the result shows that solving crystal structure of cyclodextrins inclusion complexes of such complexity is accessible to powder diffractionists to some extent.

Thermodynamic, IR spectral and X-ray diffraction studies of the "β-cyclodextrin-para-aminobenzoic acid" inclusion complex

The inclusion complex with stoichiometric composition 1:1 was formed as a result of intermolecular interactions between para-aminobenzoic acid and β-cyclodextrin. The stability constant of "β-cyclodextrinpara- aminobenzoic acid" inclusion complex at 289,

Host-guest system of Vitamin B10 in β-cyclodextrin: Characterization of the interaction in solution and in solid state

Conventional drugs are usually formulated for the immediate release of the medicinal substances and for obtaining the desired therapeutic effect. The aim of this paper was to investigate the possible interactions between Vitamin B10 and β-cyclodextrin (β-

Crystal structure of cyclomaltoheptaose (β-cyclodextrin) complexes with p-aminobenzoic acid and o-aminobenzoic acid

Crystal structures of cyclomaltoheptaose (β-cyclodextrin) complexes with p-aminobenzoic acid and o-aminobenzoic acid have been determined by single-crystal X-ray diffraction. The space group of the β-cyclodextrin-p-aminobenzoic acid complex is P21 with a host:guest stoichiometry of 1:1, and that of the β-cyclodextrin-o-aminobenzoic acid complex is P1 with a stoichiometry of 2:3. The different structures of the guest molecules lead to the different molecular packing structures of the two complexes. Intermolecular hydrogen-bond interactions are the main force that stabilize the supramolecular systems. In both crystals, there are water molecules located near the cavity rims and in interstices between molecules of β-cyclodextrin participating in formation of intermolecular hydrogen bonds.

Volumetric and calorimetric study on complex formation of cyclodextrins with aminobenzoic acids

A volumetric and calorimetric study on the complex formation of α- and β-cyclodextrins with isomeric aminobenzoic acids in water at 298.15 K revealed the noticeable influence of reagent structure on the driving forces and thermodynamic parameters of bindi