80073-10-5

Basic information

• Product Name: 5-acetamido-6-hydroxynaphthalene-2-sulphonic acid
• Synonyms: 5-acetamido-6-hydroxynaphthalene-2-sulphonic acid;N-acetyl-(1-amino-2-naphthol-6-sulfonic acid);5-Acetylamino-6-hydroxy-2-naphthalenesulfonic acid
• CAS NO: 80073-10-5
• Molecular Formula: C₁₂H₁₁NO₅S
• Molecular Weight: 281.28444
• EINECS: 279-389-6
• Mol File: 80073-10-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.581g/cm³
• Refractive Index: 1.706
• CAS DataBase Reference: 5-acetamido-6-hydroxynaphthalene-2-sulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-acetamido-6-hydroxynaphthalene-2-sulphonic acid(80073-10-5)
• EPA Substance Registry System: 5-acetamido-6-hydroxynaphthalene-2-sulphonic acid(80073-10-5)

Safety Data

• Hazardous Substances Data: 80073-10-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H11NO5S/c1-7(14)13-12-10-4-3-9(19(16,17)18)6-8(10)2-5-11(12)15/h2-6,15H,1H3,(H,13,14)(H,16,17,18)

Upstream product

• 5639-34-9 5-amino-6-hydroxy-2-naphthalenesulphonic acid 
• 14090-74-5 1-nitroso-2-hydroxy-naphthalene-6-sulphonic acid 
• 93-01-6 2-naphthol-6-sulfonic acid 

Downstream Products

• 93-01-6 2-naphthol-6-sulfonic acid 

Relevant articles and documents

Process for the preparation of 1-amino-2-ethoxy-naphthalene-6-sulphonic acid

A process for the preparation of 1-amino-2-ethoxy-naphthalene-6-sulphonic acid from 2-hydroxy-naphthalene-6-sulphonic acid which comprises: A. contacting 2-hydroxy-naphthalene-6-sulphonic acid with at least an equimolar amount of an alkali metal nitrite in aqueous solution or suspension in the presence of hydrochloric acid, solution or suspension having a pH in the range of 2 to 5 and being at a temperature of 0° to 20° C.; B. reducing the reaction product of step A in an aqueous suspension by contacting the same with excess iron in the presence of at least an equivalent amount of iron-II ions, relative to the reaction product obtained according to step A, in the presence of a mineral acid at a temperature from 50° to 120° C., and treating the thus-obtained reaction mixture with aqueous alkali metal hydroxide in the presence of iron oxide; C. contacting the product of step B with excess acetic anhydride in an aqueous solution or suspension at a pH in the range of 3 to 10 at a temperature from 0° to 100° C.; D. contacting the product of step C with an ethylating agent in the presence of an acid binding agent in an aqueous-organic solvent or diluent in a pH range from 8 to 14 at a temperature from 20° to 150° C.; and E. deacetylating the product of step D by contacting the same at reflux with an aqueous alkali metal hydroxide.