80080-95-1

Basic information

• Product Name: 5-(2-chlorophenyl)-3-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• Synonyms: 2H-1,4-benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-
• CAS NO: 80080-95-1
• Molecular Formula: C₁₆H₁₂ClN₃O₃
• Molecular Weight: 329.7378
• Mol File: 80080-95-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 522.1°C at 760 mmHg
• Flash Point: 269.6°C
• Density: 1.46g/cm³
• Vapor Pressure: 5.34E-11mmHg at 25°C
• Refractive Index: 1.686
• CAS DataBase Reference: 5-(2-chlorophenyl)-3-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-chlorophenyl)-3-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one(80080-95-1)
• EPA Substance Registry System: 5-(2-chlorophenyl)-3-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one(80080-95-1)

Safety Data

• Hazardous Substances Data: 80080-95-1(Hazardous Substances Data)

Upstream product

• 58662-82-1 (S)-benzyl-[1-[[2-(o-chlorobenzoyl)-4-nitrophenyl]carbamoyl]ethyl]carbamate 

Relevant articles and documents

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There are presented novel pharmaceutically active substances which inhibit the intestinal resorption of cholesterol and which accordingly can be used in the control or prevention of atherosclerosis. These active substances are benzodiazepines of the formu

Benzodiazepine derivatives

This invention is directed to pharmacologically active compounds of the formula STR1 wherein R1 represents a hydrogen atom or lower alkyl group and R2 represents a halogen atom. The compounds of formula I are optically active and have the absolute configuration S at the carbon atom in the 3-position. They exhibit anthelmintic, sedative, anticonvulsant and muscle relaxant activity. Also provided are methods for their preparation and formulations which incorporate the active compounds.