METHIDIUMPROPYL EDTA, also known as a combined intercalating and chelating reagent, is a chemical compound that forms an iron chelate when combined with Fe(NH4)2(SO4)2. METHIDIUMPROPYL EDTA has the ability to intercalate between DNA strands and chelate metal ions, making it a versatile tool in various applications.
80082-09-3
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Basic information
- Product Name: METHIDIUMPROPYL EDTA
- Synonyms: METHIDIUMPROPYL EDTA;METHIDIUMPROPYL-EDTA FOR MOLECULAR &;EDTA methidiumpropylamide
- CAS NO:80082-09-3
- Molecular Formula: C17H18BrN5O
- Molecular Weight: 388.26172
- EINECS: N/A
- Product Categories: N/A
- Mol File: 80082-09-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: METHIDIUMPROPYL EDTA(CAS DataBase Reference)
- NIST Chemistry Reference: METHIDIUMPROPYL EDTA(80082-09-3)
- EPA Substance Registry System: METHIDIUMPROPYL EDTA(80082-09-3)
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Safety Data
- Hazard Codes: Xi
- Statements: 36/37/38
- Safety Statements: 26-36
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 80082-09-3(Hazardous Substances Data)
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80082-09-3 Usage
Uses
Used in Molecular Biology Research:METHIDIUMPROPYL EDTA is used as a footprinting probe for studying the interactions between DNA and proteins. The iron chelate formed by adding Fe(NH4)2(SO4)2 to METHIDIUMPROPYL EDTA causes random oxidative cleavage of DNA in the presence of O2 and a reducing agent. This activity allows researchers to visualize and analyze the binding sites of proteins on DNA, providing valuable insights into gene regulation and other biological processes.
Used in Analytical Chemistry:
METHIDIUMPROPYL EDTA is used as a chelating agent for the detection and analysis of metal ions. Its ability to bind metal ions can be utilized in various analytical techniques, such as spectrophotometry, chromatography, and electrophoresis, to improve the sensitivity and selectivity of metal ion detection.
Used in Environmental Science:
METHIDIUMPROPYL EDTA can be used as a tool for studying the environmental impact of metal pollution. Its chelating properties enable it to bind and sequester metal ions, which can help in assessing the extent of metal contamination in soil, water, and air samples.
Used in Pharmaceutical Development:
METHIDIUMPROPYL EDTA has potential applications in the development of new drugs and drug delivery systems. Its ability to intercalate between DNA strands and chelate metal ions can be harnessed to design drugs that target specific genetic sequences or metal-dependent enzymes, leading to the development of more effective and targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 80082-09-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,0,8 and 2 respectively; the second part has 2 digits, 0 and 9 respectively.Calculate Digit Verification of CAS Registry Number 80082-09:
(7*8)+(6*0)+(5*0)+(4*8)+(3*2)+(2*0)+(1*9)=103
103 % 10 = 3
So 80082-09-3 is a valid CAS Registry Number.
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METHIDIUMPROPYL EDTA
