80082-18-4Relevant articles and documents
Pyrimidopyridazines. 5. Summary of Cyclizations with Vicinally Functionalized Reagents and Studies of the Reductive Behavior of the Ring System
Morrison, Robert W.,Styles, Virgil L.
, p. 674 - 680 (2007/10/02)
New syntheses of pyrimidopyridazines from 6-hydrazinoisocytosines and vicinal carbonyl reagents and reduction studies with selected members of this compound series are reported.Structural features required for pyrimidopyridazine formation from reactions of 2-amino-4-hydrazinopyrimidines with vicinal difunctional reagents and selectivity with respect to product substituent orientations are summarized.