80086-22-2Relevant articles and documents
Visible-light-enhanced ring opening of cycloalkanols enabled by br?nsted base-tethered acyloxy radical induced hydrogen atom transfer-electron transfer
Zhao, Rong,Yao, Yuan,Zhu, Dan,Chang, Denghu,Liu, Yang,Shi, Lei
supporting information, p. 1228 - 1231 (2018/02/23)
A metal-free ring opening/halogenation of cycloalkanols, which combines both PPO/TBAX oxidant system and blue LEDs irradiation, is presented. This method produces diverse γ, α, and even more remotely halogenated ketones in moderate to excellent yields under mild conditions. Interestingly, experimental and computational studies demonstrate the novel ring size-dependent concerted/stepwise (four-/five- to eight-membered rings) hydrogen atom transfer-electron transfer induced by Br?nsted base-tethered acyloxy radical, which indicates distinct advantages brought by the cyclic structure of diacyl peroxides.
TETRAZOLE DERIVATIVES, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME
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, (2008/06/13)
Tetrazole derivatives of the formula: STR1 wherein R 1 is a lower alkykl, phenyl or a group of the formula:--S(O) l--A--(X) m--R 3, and R 2 is hydrogen, a lower alkyl, phenyl or a cycloalkyl when R 1 is the group--S(O) l--A--(X) m--R 3, or R 2 is a group of the formula:--B--CO--R 4 when R 1 is a lower alkyl or phenyl and a pharmaceutically acceptable salt thereof, which have prophylactic or therapeutic activities against peptic and/or duodenal ulcers and are useful as an anti-ulcer drug; processes for the preparation of the tetrazole derivatives; and pharmaceutical composition containing said tetrazole derivatives.