80090-65-9Relevant articles and documents
SOLVENT EFFECT IN THE REACTION OF (S)-N-ISOPROPYL-(Nα-BENZYLOXYCARBONYL)PROLINAMIDE WITH LITHIUM ALUMINUM HYDRIDE
Kiyooka, Syun-ichi,Goto, Fumitaka,Suzuki, Kojiro
, p. 1429 - 1430 (2007/10/02)
A specific solvent effect in the reduction of (S)-N-isopropyl-(Nα-benzyloxycarbonyl)prolinamide with lithium aluminum hydride.The reactions in diethyl ether gave mainly (S)-N-isopropyl-(Nα-methyl)prolinamide and (2S)-N-methyl-2-pyrrolidine, while 3-isopropyl-2-oxo-1,3-diazabicyclooct-4-ene and (5S)-3-isopropyl-1,3-diazabicyclooctane were produced in tetrahydrofuran.