80098-87-9Relevant academic research and scientific papers
Efficient Synthesis of 3,6-Dihydro-2H-pyrans via [3+2+1] Annulation Based on the Heteroatom-free Tri-atom Donor
Li, Hui,Liu, Haiping,Liu, Yufeng,Cao, Zhongzhong,Su, Miaodong,Fu, Meiqiang,Luo, Weiping,Liu, Qiang,Guo, Cancheng
supporting information, p. 5392 - 5399 (2019/11/11)
A new [3+2+1] annulation strategy based on the heteroatom-free tri-atom donor to synthesize 3,6-dihydro-2H-pyrans has been developed. In this method, 2-arylpropylene served as tri-atom donor to contribute three carbon atoms, the heteroatom was provided by aldehyde, and DMSO served as one carbon donor and solvent. This annulation reaction gave 3,6-dihydro-2H-pyrans in moderate to good yields. Based on the control experiments, a possible mechanism was proposed. (Figure presented.).
SYNTHESIS OF SUBSTITUTED 5,6- AND 3,6-DIHYDRO-2H-PYRANS BY ACID CONDENSATION OF ISOBUTYLENE AND α-METHYLSTYRENE WITH ALIPHATIC ALDEHYDES
Romanov, N. A.,Kantor, E. A.,Karakhanov, R. A.,Rakhmankulov, D. L.
, p. 351 - 354 (2007/10/02)
2,4-Disubstituted dihydropyrans, isomeric with respect to the position of the double bond, were obtained by the reaction of isobutylene and α-methylstyrene with formaldehyde and aliphatic aldehydes.
PRODUCTION OF SUBSTITUTED 5,6- AND 3,6-DIHYDRO-2H-PYRANS FROM 4,4-DIMETHYL- AND 4-METHYL-4-PHENYL-1,3-DIOXANES AND CARBONYL COMPOUNDS
Romanov, N. A.,Kantor, E. A.,Musavirov, R. S.,Karakhanov, R. A.,Rakhmankulov, D. L.
, p. 1576 - 1581 (2007/10/02)
2,4-Disubstituted and 2,2,4-trisubstituted dihydropyrans, isomeric with respect to the position of the double bond, were obtained by the reaction of 4,4-dimethyl- and 4-methyl-4-phenyl-1,3-dioxanes with aldehydes and ketones.The effects of temperature and of the amount and nature of the catalyst on the direction and selectivity of the reaction were investigated.
