80120-35-0

Usage

InChI:InChI=1/C14H18O3/c1-3-5-6-11-7-9-12(10-8-11)13(15)14(16)17-4-2/h7-10H,3-6H2,1-2H3

Upstream product

• 41492-05-1 p-bromobutylbenzene 
• 95-92-1 oxalic acid diethyl ester 
• 1156-55-4 N-(4-butylphenyl)-4-methylbenzenesulfonamide 
• 2999-46-4 Ethyl isocyanoacetate 

Downstream Products

• 1346946-70-0 3-(2-(4-butylphenyl)acryloyl)oxazolidin-2-one 
• 1346947-82-7 C₂₂H₂₅NO₃S 
• 1289643-00-0 (R,E)-ethyl 2-[(tert-butylsulfinyl)imino]-2-(4-butylphenyl)acetate 
• 1289643-11-3 (R)-ethyl 2-(4-butylphenyl)-2-[(R)-1,1-dimethylethylsulfinamido]acetate 

Relevant academic research and scientific papers

Palladium-Catalyzed Asymmetric Hydroesterification of α-Aryl Acrylic Acids to Chiral Substituted Succinates

A palladium-catalyzed asymmetric hydroesterification of α-aryl acrylic acids with CO and alcohol was developed, preparing a variety of chiral α-substituted succinates in moderate yields with high ee values. The kinetic profile of the reaction progress revealed that the alkene substrate first underwent the hydroesterification followed by esterification with alcohol. The origin of the enantioselectivity was elucidated by density functional theory computation.

Destruction and Construction: Application of Dearomatization Strategy in Aromatic Carbon-Nitrogen Bond Functionalization

The formation of carbon-carbon bonds through the functionalization of aromatic carbon-nitrogen bonds is a highly attractive synthetic strategy in the synthesis of aromatic molecules. In this paper, we report a novel aromatic carbon-nitrogen bond functionalization reaction by using a simple dearomatization strategy. Through this process para-substituted anilines serve as a potential aryl source in the construction of a range of functionalized aromatic molecules, such as quaternary carbon centers, α-keto esters, and aldehydes.

Enantioselective enolate protonation in sulfamichael addition to r-substituted n-acryloyloxazolidin-2-ones with bifunctional organocatalyst

Organocatalytic conjugate addition of thiols to R-substituted N-acryloyloxazolidin-2-ones followed by asymmetric protonation has been studied in the presence of cinchona alkaloid derived thioureas. Both of the enantiomers are accessible with the same level of enantioselectivity using pseudoenantiomeric quinine/quinidine derived catalysts. The addition/protonation products have been converted to useful biologically active molecules. 2011 American Chemical Society.