80129-81-3Relevant academic research and scientific papers
ETUDE COMPARATIVE DE LA REACTIVITE DES ACRIDANONES, DES AMINOACRIDINES ET DES THIOACRIDANONES VIS-A-VIS DES AGENTS D'ALKYLATION DANS LES CONDITIONS DE LA CATALYSE PAR TRANSFERT DE PHASE
Galy, J. P.,Vincent, E. J.,Galy, A. M.,Barbe, J.,Elguero, J.
, p. 947 - 954 (2007/10/02)
This paper describes the results obtained in the alkylation of thioacridanone under phase transfer catalysis conditions.Nine different alkylating agents have been used and in all the cases the thioether was the sole product obtained.Proton and carbon-13 n.m.r. study of the different compounds has been carried out, giving an useful criteria to differentiate thioethers and thioacridanones.The HSAB principle has been used to discuss the relative amounts of 9- and 10- substituted isomers obtained from acridanones, aminoacridines and thioacridanones using different alkylating and acylating agents.
