80140-41-6Relevant academic research and scientific papers
Configuration and conformational study of some 2-aryl-trans-decahydroquinolin-4-ones
Bhavani,Natarajan
, p. 582 - 586 (2007/10/03)
The assignments of the proton and carbon signals and conformations of substituted 2-aryl-trans-decahydroquinolin-4-ones were determined using a combination of 1H, 13C, COSY and HETCOR spectral data. Analysis of the spectral data reveals that these compounds exist predominantly in twin-chair conformations with the aryl and alkyl substituents in the equatorial orientation. Introduction of an alkyl group at C-3 causes a flattening of the ring about the C-2 - C-3 bond. From the proton-proton coupling constants (J9, 10,) the junction between the rings is found to be trans.
Synthesis of 2-Aryl- and 2-Aryl-3-methyl-decahydroquinolin-4-ones
Baliah, V.,Natarajan, A.
, p. 830 (2007/10/02)
Δ1-Acetylcyclohexene and Δ1-propionylcyclohexene condense with aromatic aldehydes and ammonium acetate in ethanol to yield 2-aryldecahydroquinolin-4-ones (I) and 3-methyl-2-aryldecahydroquinolin-4-ones (II), respectively.
