80144-56-5 Usage
Uses
Used in Pharmaceutical Research:
2-(pyridin-4-yl)-1-[2-(pyridin-2-yl)ethyl]-1H-benzimidazole is used as a research compound for its potential to interact with protein targets, which may be involved in various cellular signaling pathways or enzymatic processes. Its application in this field is driven by the need to discover new molecules with therapeutic potential.
Used in Drug Development:
In the pharmaceutical industry, 2-(pyridin-4-yl)-1-[2-(pyridin-2-yl)ethyl]-1H-benzimidazole is utilized as a lead compound in drug development. 2-(pyridin-4-yl)-1-[2-(pyridin-2-yl)ethyl]-1H-benzimidazole's structure and potential interactions with biological targets make it a candidate for further optimization and testing to develop new therapeutic agents.
Used in Chemical Synthesis:
2-(pyridin-4-yl)-1-[2-(pyridin-2-yl)ethyl]-1H-benzimidazole may also be used as a building block or intermediate in the synthesis of more complex molecules with specific biological activities. Its role in this application is to provide a structural foundation for the creation of novel compounds with tailored properties for various applications in medicine and biology.
Note: Since the provided materials do not specify particular applications or industries for 2-(pyridin-4-yl)-1-[2-(pyridin-2-yl)ethyl]-1H-benzimidazole, the uses listed are general and based on the compound's potential properties and common applications of similar compounds in the fields of research and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 80144-56-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,1,4 and 4 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 80144-56:
(7*8)+(6*0)+(5*1)+(4*4)+(3*4)+(2*5)+(1*6)=105
105 % 10 = 5
So 80144-56-5 is a valid CAS Registry Number.
80144-56-5Relevant academic research and scientific papers
ACIDIC PROPERTIES OF BENZIMIDAZOLES AND SUBSTITUENT EFFECTS. V. PROTECTION OF BENZIMIDAZOLES BY N-ALKYL BOND FORMATION USING VINYLPYRIDINES
Ichikawa, Masataka,Yamamoto, Chiyuki,Hisano, Takuzo
, p. 3042 - 3047 (2007/10/02)
Vinylpyridines were utilized for protection of the benzimidazole N-H bond to give 1-(2-pyridylethyl)-benzimidazoles.The reaction was found to progress smoothly when glacial acetic acid was used as a catalyst.In the alkylation of 5- or 7-substituted-2-arylbenzimidazoles with vinylpyridines, the yield decreased with increasing electron-attracting effect of the substituent groups in the benzimidazole ring.On the other hand, the removal of pyridylethyl groups by the use of aluminum chloride as a catalyst was kinetically examined; a large excess of sodium hydroxide was used for decomposition of the intermediate adduct of aluminum chloride.The rate increased somewhat when electron-releasing substituent groups were present in the benzimidazole ring. 1--2-arylbenzimidazoles were resistant to removal of their (2-pyridyl)ethyl groups. 4-Vinylpyridine can be used more efficiently as a protecting agent.Keywords: 2-pyridylbenzimidazoles; protection with vinylpyridines for imidazole; 1-(2-pyridylethyl)-benzimidazoles; substituent effect on N-alkylation of benzimidazoles; rate of removal of pyridylethyl groups by aluminum chloride catalyst
