80158-60-7

Upstream product

• 80162-24-9 syn-(E)-2-(1-Isochinolyl)-1-(4-methylphenyl)ethanonoxim 
• 80158-40-3 2-(1-Isochinolyl)-1-(4-methylphenyl)ethanon 
• 77123-58-1 2-[2-(trimethylsilyl)ethynyl]benzaldehyde 
• 1361106-96-8 N'-(2-((trimethylsilyl)ethynyl)-benzylidene)-4-methylbenzenesulfonohydrazide 
• 766-97-2 4-n-methylphenylacetylene 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 104-85-8 para-methylbenzonitrile 
• 1721-93-3 1-methylisoquinoline 

Relevant academic research and scientific papers

[Cu(maloNHC)]-catalyzed synthesis of 2-aryl pyrazolo[5,1-a]isoquinolines by annulation of N′-(2-((trimethylsilyl)ethynyl)benzylidene)hydrazides with terminal aromatic alkynes

A [Cu(maloNHC)]-catalyzed synthesis of 2-aryl pyrazolo[5,1-a]isoquinolines via annulation of N′-(2-((trimethylsilyl)ethynyl)benzylidene)hydrazides with terminal aromatic alkynes was developed.

Ring Closures of syn-(E)- and anti-(E)-(2-Quinolylmethyl)- and -(1-Isoquinolylmethyl)ketoximes to Pyrazoloquinolines and Pyrazoloisoquinolines

The (2-quinolylmethyl)- and (1-isoquinolylmethyl)ketoximes 2a-e and 4a-d have been prepared and the oxime configurations determined.The Pyrazoloquinolines 7a, b and the pyrazoloisoquinoline 8a are formed by Beckmann reaction of the anti-isomers 2a, b and 4a, while O-mesitylsulfonylhydroxylamine yields the pyrazolo compounds 7 and 8, independent of the oxime configuration.