80165-16-8

Basic information

• Product Name: Z-Leu-Met-Leu-NH₂
• CAS NO: 80165-16-8
• Molecular Weight: 508.682
• Mol File: 80165-16-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Z-Leu-Met-Leu-NH₂(CAS DataBase Reference)
• NIST Chemistry Reference: Z-Leu-Met-Leu-NH₂(80165-16-8)
• EPA Substance Registry System: Z-Leu-Met-Leu-NH₂(80165-16-8)

Safety Data

• Hazardous Substances Data: 80165-16-8(Hazardous Substances Data)

Upstream product

• 687-51-4 H-L-Leu-NH₂ 
• 16869-44-6 N-benzyloxycarbonyl-L-leucyl-L-methionine methyl ester 
• 18830-16-5 Z-Leu-Met-OH 
• 10466-61-2 (2S)-amino-4-methylpentanamide hydrochloride 

Relevant articles and documents

Peptide Synthesis by Means of Immobilized Enzymes II. Immobilized Trypsin, Thermolysin and Papain

Model studies were performed on the utility of covalently immobilized trypsin, thermolysin and papain for peptide bond formation.Trypsin and thermolysin catalyzed the formation of peptide bonds with nearly the same efficiency as the soluble proteases and they could be re-used successfully for further coupling experiments.The possibility of using immobilized trypsin and papain for kinetically controlled peptide bond formation was investigated.With the serine type enzyme trypsin excellent product yields were obtained starting with ester carboxyl components and an economical ratio of substrates.Experiments with the thiol protease papain were unsatisfactory because the once formed product is hydrolyzed as fact as the starting ester substrate used. - Keywords: Immobilized enzymes; Papain; Peptide synthesis; Thermolysin; Trypsin