80166-50-3 Usage
Uses
Used in Chemical Synthesis:
N-(N-P-Nitro-Benzyloxycarbonyl)-Formimidoyl-2-Aminoethylthiol is used as a reagent in chemical synthesis for the protection and deprotection of amine groups. This process is crucial for the synthesis of various bioactive compounds and pharmaceuticals, ensuring that the amine groups are protected during the reaction and then selectively deprotected when needed.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-(N-P-Nitro-Benzyloxycarbonyl)-Formimidoyl-2-Aminoethylthiol is utilized in the preparation of peptides and peptidomimetics. Its ability to protect and deprotect amine groups is essential for the synthesis of these complex molecules, which have potential applications in drug development and therapeutics.
Overall, N-(N-P-Nitro-Benzyloxycarbonyl)-Formimidoyl-2-Aminoethylthiol is an important chemical compound that contributes to the development and production of various bioactive compounds and pharmaceuticals, particularly in the synthesis of peptides and peptidomimetics.
Check Digit Verification of cas no
The CAS Registry Mumber 80166-50-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,1,6 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 80166-50:
(7*8)+(6*0)+(5*1)+(4*6)+(3*6)+(2*5)+(1*0)=113
113 % 10 = 3
So 80166-50-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3O4S/c15-11(13-8-12-5-6-19)18-7-9-1-3-10(4-2-9)14(16)17/h1-4,8,19H,5-7H2,(H,12,13,15)
80166-50-3Relevant academic research and scientific papers
A DIRECT TRANSFORMATION OF BICYCLIC KETO ESTERS TO N-FORMIMIDOYL THIENAMYCIN
Shinkai, I.,Reamer, R. A.,Hartner, F. W.,Liu, T.,Sletzinger, M.
, p. 4903 - 4906 (2007/10/02)
A convenient direct transformation of p-nitrobenzyl 6-(1'-hydroxyethyl)-azabicyclo-(3.2.0)heptane-3,7-dione-2-carboxylate to N-formimidoyl thienamycin utilizing the silylated derivative of N-formimidoyl cysteamine is described.
Process for the preparation of N-protected N-formimidoyl 2-aminoethanethiol
-
, (2008/06/13)
Disclosed is 2 and a process for its preparation: STR1 It is useful in the synthesis of N-formimidoyl thienamycin; R2 is hydrogen or a protecting group.
