80171-20-6Relevant articles and documents
Ring Monofluorinated Hydroxypyrazoles
Kagaruki, Serry R. F.,Kitazume, Tomoya,Ishikawa, Nobuo
, p. 3221 - 3222 (2007/10/02)
3-Alkyl(or aryl)-4-fluoro-5-hydroxypyrazoles and their 1-methyl derivatives were prepared by the reaction of methyl α-fluoro-β-alkyl(or aryl)-β-keto esters with hydrazine hydrate or methylhydrazine in ethanol.The reaction of arylhydrazines with α-fluoro-β-keto esters gave only hydrazones which could not be cyclized to pyrazoles.