80172-07-2Relevant academic research and scientific papers
Preparation of fluorine-containing diphenyl ethers
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, (2008/06/13)
A method of preparing a diphenyl ether compound of the formula (II) STR1 wherein X is F, Cl or Br; Z is hydrogen, halogen, NO2 of CN; and W is methyl, cyano, CH3 CO--, or a group --C--OR, wherein R is --OH; --OM wherein M is a cation; OR1 wherein R1 is an optionally substituted aliphatic radical; --NR2 R3 wherein R2 and R3 are each hydrogen or an optionally substituted aliphatic radical; or --NHSO2 R4 wherein R4 is alkyl of 1 to 6 carbon atoms, which comprises reacting a 3-X-substituted-4,5-difluorobenzotrifluoride with a salt of a 3,4-W,Z-substituted phenol. The invention further comprises novel 3-X-4,5-difluorobenzotrifluorides for use in the process.
