80178-35-4

Basic information

• Product Name: 2-Hexanone, 6-hydroxy-1-(triphenylphosphoranylidene)-
• CAS NO: 80178-35-4
• Molecular Formula: C24H25O2P
• Molecular Weight: 376.435
• Mol File: 80178-35-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Hexanone, 6-hydroxy-1-(triphenylphosphoranylidene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hexanone, 6-hydroxy-1-(triphenylphosphoranylidene)-(80178-35-4)
• EPA Substance Registry System: 2-Hexanone, 6-hydroxy-1-(triphenylphosphoranylidene)-(80178-35-4)

Safety Data

• Hazardous Substances Data: 80178-35-4(Hazardous Substances Data)

Upstream product

• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 19493-09-5 Methylenetriphenylphosphorane 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 157021-75-5 6-(tert-butyl-dimethyl-silanyloxy)-1-(triphenyl-λ⁵-phosphanylidene)-hexan-2-one 

Relevant articles and documents

The zipper-mode domino intramolecular Diels-Alder reaction: A new 0 → ABCD strategy for steroids and related compounds

Four C-C bonds, four rings, and eight contiguous stereocenters in one go! Tetracyclic product 2, which results on warming simple acyclic precursor 1 with a mild Lewis acid, is formed through an efficient and highly stereoselective domino sequence of two intramolecular Diels-Alder reactions. Pharmacologically important norsteriods are just one potential application of this extremely effective approach to fused polycyclic systems.

Synthesis of a Pentacyclic Model of Ptilomycalin A

The conversion of dienes 3 and 10 into the pentacyclic guanidine compounds 6 and 11 is reported; their preparation illustrates a potentially biomimetic synthetic route to the biologically active natural product Ptilomycalin A 1.

Process for producing α,β-unsaturated ketones

Derivatives of α,β-unsaturated ketones having anticonvulsant activity and methods of their preparation from heterocyclic phosphonium salts and acyclic phosphoranes are disclosed.