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PHORBOL 12-RETINOATE 13-ACETATE, 4BETA, also known as 4β-Phorbol 12,13-didecanoate, is a synthetic derivative of phorbol, a natural compound found in the seed oil of the croton tiglium plant. It is a potent tumor promoter and an activator of protein kinase C (PKC), and has been studied for its potential use in cancer research, inducing differentiation in leukemia cells, and its potential application in the treatment of skin disorders such as psoriasis. Furthermore, it has been identified as a potent activator of immune response, making it a potential candidate for immunotherapy.

80188-99-4

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80188-99-4 Usage

Uses

Used in Cancer Research:
PHORBOL 12-RETINOATE 13-ACETATE, 4BETA is used as a research tool for studying the mechanisms of tumor promotion and the role of protein kinase C (PKC) in cancer development. Its ability to induce differentiation in leukemia cells makes it a valuable compound for investigating the potential therapeutic effects of differentiating agents in cancer treatment.
Used in Skin Disorder Treatment:
In the pharmaceutical industry, PHORBOL 12-RETINOATE 13-ACETATE, 4BETA is used as a potential treatment for skin disorders such as psoriasis. Its tumor-promoting properties may help in the development of new therapies for skin conditions that require modulation of cell growth and differentiation.
Used in Immunotherapy:
PHORBOL 12-RETINOATE 13-ACETATE, 4BETA is used as a potent activator of immune response in the field of immunotherapy. Its ability to stimulate the immune system makes it a promising candidate for the development of new treatments for various diseases, including cancer and infectious diseases, by enhancing the body's natural defense mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 80188-99-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,1,8 and 8 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 80188-99:
(7*8)+(6*0)+(5*1)+(4*8)+(3*8)+(2*9)+(1*9)=144
144 % 10 = 4
So 80188-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C42H56O8/c1-24(16-17-31-26(3)15-12-18-38(31,7)8)13-11-14-25(2)19-34(45)49-37-28(5)41(48)32(35-39(9,10)42(35,37)50-29(6)44)21-30(23-43)22-40(47)33(41)20-27(4)36(40)46/h11,13-14,16-17,19-21,28,32-33,35,37,43,47-48H,12,15,18,22-23H2,1-10H3/b14-11+,17-16+,24-13+,25-19+/t28-,32+,33-,35-,37-,40-,41-,42-/m1/s1

80188-99-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name PHORBOL 12-RETINOATE 13-ACETATE, 4BETA

1.2 Other means of identification

Product number -
Other names 12-o-retinoylphorbol-13-acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80188-99-4 SDS

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