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Ringer's lactate, also known as Lactated Ringer's solution or Hartmann's solution, is a medical fluid solution introduced by Sidney Ringer in 1880 and later modified by Alex Hartmann in the 1930s. It is designed to promote the contraction of isolated frog hearts and contains potassium, calcium, and sodium in a lactate buffer solution. The solution has less sodium than isotonic saline and more closely approximates plasma chloride levels.

8022-63-7

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8022-63-7 Usage

Uses

Used in Medical Industry:
Ringer's lactate is used as a fluid replacement therapy for various medical conditions, including hypovolemia, dehydration, and electrolyte imbalances. It helps maintain fluid and electrolyte balance in the body and is particularly useful in treating metabolic acidosis due to its lactate buffer.
Used in Surgical Procedures:
Ringer's lactate is used as an intravenous fluid during surgical procedures to maintain blood volume and pressure, and to prevent complications such as hypovolemic shock.
Used in Emergency Medicine:
Ringer's lactate is used as a resuscitation fluid in emergency medicine to treat patients with severe injuries, burns, or other conditions that cause significant fluid loss.
Used in Critical Care:
Ringer's lactate is used in critical care settings to support patients with compromised cardiovascular function or those who require fluid management due to various medical conditions.
Used in Research:
Ringer's lactate is used as a physiological solution in laboratory research, particularly in studies involving isolated organs or tissues, to maintain their normal function and viability.

Indications

1. Ringer's lactate can be used as a replacement fluid in burns and post-operative patients.2. lt can be safely used for initial treatment of diarrhoea induced dehydration in paediatric patients. Hypovolaemia with hypokalaemic metabolic acidosis induced by diarrhoea is effectively treated with Ringer's lactate.3. Sodium lactate in Ringer's lactate is metabolised in the liver to bicarbonate, making it useful in the correction of metabolic acidosis.4. Ringer's lactate is very useful in many surgical conditions because it provides bicarbonate with all electrolytes.5. Ringer's lactate corrects metabolic acidosis, provides dextrose free water with added advantage of supplying potassium.6. lt can be used instead of isotonic saline during surgery or in the initial management of the injured or wounded patient.

Pharmacology

1. Ringer's lactate is the most physiological fluid.Larger amounts of Ringer's lactate can be infused rapidly without risk of electrolyte imbalance as its electrolyte content (i.e. Na, K, and Ca) is nearly similar to the free concentration in plasma.2. Ringer's lactate has a high sodium concentration 130 mEq/litre, so it rapidly expands intravascular volume like isotonic saline.

Precautions

1. There will be formation of clots in the donor blood if Ringer's lactate is given with blood transfusion simultaneously.This is due to inactivation of the anticoagulant by binding with calcium present in Ringer's lactate.Therefore, simultaneous infusion of Ringer's lactate and blood product in same intravenous line is contraindicated.2. Ringer's lactate does not have the colloid osmotic effect to replace plasma so it should not be given during severe blood loss as a plasma substitute.3. Ringer's lactate is unsuitable for routine use as a sole intravenous fluid in the post-operative period due to high electrolyte content.

Check Digit Verification of cas no

The CAS Registry Mumber 8022-63-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 8,0,2 and 2 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 8022-63:
(6*8)+(5*0)+(4*2)+(3*2)+(2*6)+(1*3)=77
77 % 10 = 7
So 8022-63-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H6O3.Ca.4ClH.K.2Na/c1-2(4)3(5)6;;;;;;;;/h2,4H,1H3,(H,5,6);;4*1H;;;/q;+2;;;;;+1;;+1/p-4

8022-63-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name calcium,potassium,sodium,2-hydroxypropanoic acid,sodium,tetrachloride

1.2 Other means of identification

Product number -
Other names Ringer-lactate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:8022-63-7 SDS

8022-63-7Upstream product

8022-63-7Downstream Products

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