80227-73-2

Basic information

• Product Name: Benzenepropanol, alpha-1-propenyl-
• Synonyms: Benzenepropanol, alpha-1-propenyl-
• CAS NO: 80227-73-2
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 0
• Mol File: 80227-73-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenepropanol, alpha-1-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanol, alpha-1-propenyl-(80227-73-2)
• EPA Substance Registry System: Benzenepropanol, alpha-1-propenyl-(80227-73-2)

Safety Data

• Hazardous Substances Data: 80227-73-2(Hazardous Substances Data)

Upstream product

• 3277-89-2 phenethylmagnesium bromide 
• 123-73-9 crotonaldehyde 
• 88842-01-7 5-Phenyl-1-(phenylselenonyl)-1-penten-3-ol 
• 56539-56-1 (E)-6-Phenyl-hex-3-en-2-ol 

Downstream Products

• 1461649-09-1 (S,E)-1-phenylhex-4-en-3-ol 
• 60550-53-0 1-phenyl-4-hexen-3-one 
• 77605-17-5 (Z)-hexa-3,5-dien-1-ylbenzene 
• 39669-95-9 (E)-hexa-3,5-dien-1-ylbenzene 

Relevant articles and documents

Copper-Catalyzed Enantioselective Conjugate Addition to α,β-Unsaturated Aldehydes with Various Organometallic Reagents

β-Substituted aldehydes constitute a very important class of compounds found in nature. Synthesis of this motif can be envisioned by C-C bond formation on enals. For this purpose, we report herein the development of enantioselective copper-catalyzed conjugate addition of various organometallic reagents to α,β-unsaturated aldehydes with (R)-H8BINAP, (R)-TolBINAP, and (R)-SEGPHOS as chiral ligands. Three sets of conditions were successfully developed and several enals were used. Reactivity and regio- and enantioselectivities were strongly dependent on reaction conditions and substrates. Good to excellent regio- and enantioselectivities were obtained with zinc reagents R2Zn and aluminum reagents R3Al. However, the asymmetric conjugate addition of Grignard reagents afforded only moderate to good regio- and enantioselectivities.

Rearrangement of allylic and propargylic alcohols catalyzed by the combined use of tetrabutylammonium perrhenate(VII) and p-toluenesulfonic acid

Allylic rearrangement and/or dehydration reaction of allylic alcohols proceeds smoothly by the use of catalytic amounts of tetrabutylammonium perrhenate and p-toluenesulfonic acid hydrate. Treatment of propargylic alcohols with the catalysts at room temperature affords the rearranged products, α,β-unsaturated carbonyl compounds, while β,γ-unsaturated ketones are obtained as main products by the reaction in refluxing 1,2-dichloroethane. The application of this catalytic system is also described for the preparation of some synthetic intermediates.

Reactions of 3-Hydroxyvinyl Selenones with Alkoxides. Oxetane Formation and Fragmentation Reactions

3-Hydroxyvinyl phenyl selenones are prepared and their behavior as conjugate addition acceptors has been investigated.As a result, a selenonyl group has been found to activate the C=C bond for conjugate addition of nucleophiles and further to behave as an