80231-48-7Relevant academic research and scientific papers
Metal free TBHP-promoted intramolecular carbonylation of arenes: Via radical cross-dehydrogenative coupling: Synthesis of indenoquinolinones, 4-azafluorenones and fluorenones
Mishra, Kalpana,Pandey, Ashok Kumar,Singh, Jay Bahadur,Singh, Radhey M.
, p. 6328 - 6336 (2016/07/11)
A metal-free, TBHP-promoted economical route is developed via the sp2 C-H bond functionalization strategy for the synthesis of indenoquinolinones, 4-azafluorenones and fluorenones. Reactions provided excellent yield of the products under mild conditions. We have successfully synthesized 11H-indeno[1,2-b]quinolin-11-one, an antibacterial agent, in excellent yields.
QUINOXALINE AND QUINOLINE DERIVATIVES AS KINASE INHIBITORS
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Page/Page column 37, (2009/07/25)
A series of heteroaryl-substituted quinoxaline and quinoline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
A Versatile New Synthesis of Quinolines and Related Fused Pyridines. Part 9. Synthetic Application of the 2-Chloroquinoline-3-carbaldehydes
Meth-Cohn, Otto,Narine, Bramha,Tarnowski, Brian,Hayes, Roy,Keyzad, Amitis,at al.
, p. 2509 - 2517 (2007/10/02)
The 2-chloro-groups of the title compounds have been replaced by H, I, OH, SR, Li, CO2H, CHO, Ph, piperidine, and N3 (giving a tetrazole).The aldehyde group has also been converted into oxime, hydrazone, and acrylic acid derivatives.From these and related
