80253-44-7

Upstream product

• 80253-43-6 3-[3-(3-Amino-2,2-dimethyl-propionylamino)-2,2-dimethyl-propionylamino]-2,2-dimethyl-propionic acid ethyl ester 
• 80253-41-4 β-benzyloxycarbonylaminopivaloyl-β-aminopivaloyl-β-aminopivalic acid 
• 59193-77-0 3-amino-2,2-dimethylpropionic acid ethyl ester 
• 80253-38-9 3-amino-2,2-dimethylpropionic acid ethyl ester hydrochloride 
• 80253-36-7 3-(benzyloxycarbonylamino)-2,2-dimethylpropanoic acid 
• 80253-40-3 β-benzyloxycarbonylaminopivaloyl-β-aminopivaloyl-β-aminopivalic acid ethyl ester 
• 80253-39-0 β-benzyloxycarbonylaminopivaloyl-β-aminopivalic acid 
• 501-53-1 benzyl chloroformate 
• 2843-19-8 3-amino-2,2-dimethylpropanoic acid, hydrochloride salt 

Downstream Products

• 80253-45-8 β-benzyloxycarbonylaminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivaloyl-β-aminopivalic acid 

Relevant academic research and scientific papers

Synthesis of β-Amino-acid Peptides. Part 2. Preparation of Peptides of 2-Amino-2,2-dimethylpropionic Acid by Means of Conventional Coupling Reagents and with Oxazin-6-one Derivatives

Side reactions were encountered during the coupling of 3-amino-2,2-dimethylpropionic acid (β-Api) derivatives, some of which could be directly ascribed to steric hindrance at the carboxy-group.Protected and deprotected tri- and hexa-peptides were prepared