802541-88-4

Basic information

• Product Name: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-2-PHENYLPROPANOIC ACID
• Synonyms: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-2-PHENYLPROPANOIC ACID;(S)-BOC-ALPHA-METHYL-PHENYLGLYCINE;(S)-2-(Boc-amino)-2-phenylpropanoic acid;802541-88-4
• CAS NO: 802541-88-4
• Molecular Formula: C₁₄H₁₉NO₄
• Molecular Weight: 265.3
• Mol File: 802541-88-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-2-PHENYLPROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-2-PHENYLPROPANOIC ACID(802541-88-4)
• EPA Substance Registry System: (S)-2-(TERT-BUTOXYCARBONYLAMINO)-2-PHENYLPROPANOIC ACID(802541-88-4)

Safety Data

• Hazardous Substances Data: 802541-88-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Boc-phenylalanine is utilized as a key component in the development of new drugs and therapeutic agents. Its role in peptide synthesis is crucial for designing and constructing medicinal peptides with specific therapeutic targets and properties.
Used in Academic Research:
In academic research, Boc-phenylalanine is employed as a building block for the synthesis of novel peptide-based compounds. Researchers use its selective deprotection capabilities to explore and develop new drug candidates with potential applications in various medical fields.
Used in Materials Science:
Boc-phenylalanine also finds applications in the field of materials science. It is used in the design and synthesis of functional materials with tailored properties. These materials can be engineered for specific uses, such as in sensors, drug delivery systems, or other high-tech applications where precise control over material properties is essential.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 13398-26-0 (S)-2-methyl-2-phenylglycine 
• 208938-33-4 (S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-2-phenyl-propionaldehyde 
• 13398-55-5 (S)-4-methyl-4-phenyloxazolidin-2-one 
• 208938-37-8 tert-Butyl-((S)-2-isocyanato-2-phenyl-propoxy)-dimethyl-silane 
• 208938-35-6 (S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-2-phenyl-propionic acid 

Downstream Products

• 802541-90-8 (1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine hydrochloride 
• 802541-89-5 N-(tert-butoxycarbonyl)-(1S)-1-methyl-2-morpholin-4-yl-2-oxo-1-phenylethylamine 
• 876366-42-6 4-methyl-5-oxo-4-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

PYRAZOLO-QUINAZOLINE DERIVATIVES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS

Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.

Asymmetric synthesis of α,α-disubstituted α-amino acide derivatives using MABR promoted rearrangement

An efficient route for the asymmetric synthesis of α,α-disubstituted α-amino acids derivatives (1, 2, and 3) starting from readily available epoxy silyl ethers (6) has been developed. High enantiomeric purity can be realized by the present method using a combination of MABR rearrangement of a chiral epoxide and Curtius rearrangement.