80272-25-9Relevant academic research and scientific papers
Gold-catalyzed carboalkoxylations of 2-ethynylbenzyl ethers to form 1- and 2-indanones chemoselectively: Effects of ligands and solvents
Wang, Chiou-Dong,Hsieh, Yi-Feng,Liu, Rai-Shung
supporting information, p. 144 - 152 (2014/03/21)
The selective syntheses of 1- and 2-indan-one compounds from 2-ethynylbenzyl ethers have been achieved with suitable catalysts and solvents. The highly acidic [tris(pentafluorophenyl)phos-phine]gold hexafluoroantimonate [(C6F5)3AuSbF6] in nitromethane (MeNO2) preferably gives 1-indan-ones whereas [(ortho-biphenyl) di(tert-butyl)phosphine] gold triflimide [(tBu)2(o-biphenyl) AuNTf2] in dichloroethane tends to form 2-indanone derivatives. For 2-indanone products, we isolated two indenyl methyl ethers for deuterium labeling analyses, providing evidence for p-alkyne activation.
Gold-catalyzed oxidative cyclizations of cis-3-En-1-ynes to form cyclopentenone derivatives
Bhunia, Sabyasachi,Ghorpade, Satish,Huple, Deepak B.,Liu, Rai-Shung
supporting information; scheme or table, p. 2939 - 2942 (2012/05/20)
Golden tendencies: The title reaction for synthesizing cyclopentenone derivatives utilizes a gold complex and 8-methylquinoline oxide as the catalyst system (see scheme; IPr=1,3-bis(diisopropylphenyl)imidazol-2-ylidene). Such products are not attainable using diazocarbonyl reagents, as the gold carbenoids tend to react with C-H bonds. Copyright
